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Karine Gilbert Selected Research

1- (2- (2- (2- (2- methoxyethoxy)ethoxy)ethoxy)ethoxycarbonyloxymethyl)- 4- (N'- cyano- N''- (6- (4- chlorophenoxy)hexyl)- N- guanidino)pyridinium

11/2009The small molecule GMX1778 is a potent inhibitor of NAD+ biosynthesis: strategy for enhanced therapy in nicotinic acid phosphoribosyltransferase 1-deficient tumors.
6/2009Preclinical development of the nicotinamide phosphoribosyl transferase inhibitor prodrug GMX1777.

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Karine Gilbert Research Topics

Disease

2Neoplasms (Cancer)
11/2009 - 06/2009
1Glioblastoma (Glioblastoma Multiforme)
11/2009
1Neuroblastoma
11/2009
1Sarcoma (Soft Tissue Sarcoma)
11/2009
1Lymphoma (Lymphomas)
06/2009
1Multiple Myeloma
06/2009
1Carcinoma (Carcinomatosis)
06/2009
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
06/2009

Drug/Important Bio-Agent (IBA)

2N- (6- chlorophenoxyhexyl)- N''- cyano- N''- 4- pyridylguanidine (CHS 828)IBA
11/2009 - 06/2009
2NAD (NADH)IBA
11/2009 - 06/2009
21- (2- (2- (2- (2- methoxyethoxy)ethoxy)ethoxy)ethoxycarbonyloxymethyl)- 4- (N'- cyano- N''- (6- (4- chlorophenoxy)hexyl)- N- guanidino)pyridiniumIBA
11/2009 - 06/2009
1nicotinate phosphoribosyltransferaseIBA
11/2009
1ProdrugsIBA
11/2009
1Proteins (Proteins, Gene)FDA Link
11/2009
1Messenger RNA (mRNA)IBA
11/2009

Therapy/Procedure

1Therapeutics
11/2009
1Intravenous Injections
06/2009
1Intravenous Infusions
06/2009